TRIP10

Across TCGA patient cohorts, TRIP10 mutation is significantly associated with the RNA expression of many other genes, with 2,826 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRIP10-associated genes across cancer lineages are RNU6-166P, RN7SL813P, and HIGD1AP3. Each is linked with TRIP10 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRIP10-to-partner and partner-to-TRIP10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-166P grouped by TRIP10-low versus TRIP10-high in PRAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIP10→partner) and Y-score (partner→TRIP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PRAD	RNU6-166P →	+0.297	+7.939	<.001	.008	3	3
CESC	RN7SL813P →	+0.178	+4.103	<.001	.002	3	2
CESC	HIGD1AP3 →	+0.073	+4.144	<.001	.009	3	2
HNSC	TRAJ46 →	+0.571	+4.505	<.001	.009	3	2
BRCA	RN7SL616P →	+0.125	+5.468	.004	<.001	3	2
COAD	RNA5SP319 →	+0.560	+3.271	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,826 associations by consensus.

RNU6-166P by TRIP10 expression — PRAD

Explore this box plot interactively →