TRIP10

Across TCGA cell cohorts, TRIP10 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,760 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TRIP10-associated GO terms across cancer lineages are Cytoplasmic pattern recognition receptor signaling pathway, Actin filament organization, and Wound healing. Each is linked with TRIP10 in more than 12 cancer types. Because this analysis shows association rather than direction, both TRIP10-to-partner and partner-to-TRIP10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic pattern recognition receptor signaling pathway grouped by TRIP10-low versus TRIP10-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIP10→partner) and Y-score (partner→TRIP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Cytoplasmic pattern recognition receptor signaling pathway →	+0.066	+1.448	<.001	<.001	3	13
LIVER	Actin filament organization →	+0.110	+1.513	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Wound healing →	+0.089	+1.161	.007	.005	2	13
LUNG_NSCLC_LUSC	Protein activation cascade →	+0.267	+1.160	.003	.001	3	12
STOMACH	Positive regulation of plasma membrane repair →	+0.240	+1.076	.001	.002	2	12
SOFT_TISSUE	Canonical NF-kappaB signal transduction →	+0.077	+1.126	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,760 associations by consensus.

Cytoplasmic pattern recognition receptor signaling pathway by TRIP10 expression — BREAST

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