TRIP10

Across TCGA cell cohorts, TRIP10 mutation is significantly associated with the RNA expression of many other genes, with 264 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TRIP10-associated genes across cancer lineages are TAAR1, OR2T1, and OR6N2. Each is linked with TRIP10 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIP10-to-partner and partner-to-TRIP10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAAR1 grouped by TRIP10-low versus TRIP10-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIP10→partner) and Y-score (partner→TRIP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	TAAR1 →	+0.022	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	OR2T1 →	+0.026	+6.247	<.001	<.001	3	1
BLOOD_Lymphoma	OR6N2 →	+0.006	+5.643	.003	.002	3	1
SKIN	TMEM235 →	+0.012	+5.217	<.001	<.001	3	1
LARGE_INTESTINE	PLA2G3 →	+1.150	+3.252	<.001	.002	3	1
LARGE_INTESTINE	GCAT →	+1.137	+3.321	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 264 associations by consensus.

TAAR1 by TRIP10 expression — BLOOD_Lymphoma

Explore this box plot interactively →