TRIOBP

Across TCGA cell cohorts, TRIOBP RNA expression is significantly associated with the go_rna of many other GO terms, with 5,284 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TRIOBP-associated GO terms across cancer lineages are Actin filament capping, Negative regulation of actin filament depolymerization, and Negative regulation of actin filament polymerization. Each is linked with TRIOBP in more than 15 cancer types. Because this analysis shows association rather than direction, both TRIOBP-to-partner and partner-to-TRIOBP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Actin filament capping grouped by TRIOBP-low versus TRIOBP-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIOBP→partner) and Y-score (partner→TRIOBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Actin filament capping →	+0.230	+1.300	<.001	<.001	3	16
BONE	Negative regulation of actin filament depolymerization →	+0.195	+1.150	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Negative regulation of actin filament polymerization →	+0.152	+1.538	<.001	<.001	3	15
STOMACH	Negative regulation of protein-containing complex assembly →	+0.102	+1.147	<.001	<.001	3	15
BONE	Barbed-end actin filament capping →	+0.207	+1.015	<.001	<.001	3	15
BREAST	Caveola assembly →	+0.224	+1.333	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,284 associations by consensus.

Actin filament capping by TRIOBP expression — BONE

Explore this box plot interactively →