TRIOBP

Across TCGA cell cohorts, TRIOBP protein abundance is significantly associated with the RNA expression of many other genes, with 3,784 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TRIOBP-associated genes across cancer lineages are DOCK1, ITGA5, and EAF1. Each is linked with TRIOBP in more than 3 cancer types. Because this analysis shows association rather than direction, both TRIOBP-to-partner and partner-to-TRIOBP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRIOBP versus DOCK1 in CNS, with a Pearson correlation of -0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIOBP→partner) and Y-score (partner→TRIOBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	DOCK1 →	-0.687	-1.171	.002	.004	3	4
LUNG_SCLC	ITGA5 →	-2.075	-0.637	.004	<.001	3	4
LARGE_INTESTINE	EAF1 →	+0.997	+0.880	<.001	<.001	3	4
LUNG_NSCLC_LUSC	EIF4E →	+1.419	+1.570	<.001	.009	3	3
LUNG_NSCLC_LUAD	PLEKHA1 →	+1.070	+1.045	.006	<.001	3	3
LARGE_INTESTINE	FRS2 →	+0.976	+0.779	.005	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,784 associations by consensus.

TRIOBP vs DOCK1 — CNS

Explore this scatter interactively →