TRIOBP

Across TCGA cell cohorts, TRIOBP protein abundance is significantly associated with the go_rna of many other GO terms, with 2,316 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TRIOBP-associated GO terms across cancer lineages are Neutrophil differentiation, Polarized epithelial cell differentiation, and Negative regulation of epithelial cell apoptotic process. Each is linked with TRIOBP in more than 3 cancer types. Because this analysis shows association rather than direction, both TRIOBP-to-partner and partner-to-TRIOBP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neutrophil differentiation grouped by TRIOBP-low versus TRIOBP-high in BLOOD_Myeloma.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIOBP→partner) and Y-score (partner→TRIOBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Neutrophil differentiation →	+0.184	+1.013	.004	.005	3	4
LUNG_NSCLC_LUSC	Polarized epithelial cell differentiation →	-0.168	-1.570	.001	.009	3	4
BLOOD_Myeloma	Negative regulation of epithelial cell apoptotic process →	+0.176	+0.946	.001	.009	3	3
LARGE_INTESTINE	Cerebellum development →	-0.110	-0.716	.006	<.001	3	3
LARGE_INTESTINE	Metencephalon development →	-0.102	-0.716	.003	<.001	3	3
LUNG_NSCLC_LUSC	Positive regulation of iron ion transport →	-2.328	-1.110	<.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,316 associations by consensus.

Neutrophil differentiation by TRIOBP expression — BLOOD_Myeloma

Explore this box plot interactively →