TRIM9

Across TCGA cell cohorts, TRIM9 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TRIM9-associated genes across cancer lineages are GML, GOLGA6L1, and OR1L6. Each is linked with TRIM9 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM9-to-partner and partner-to-TRIM9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GML grouped by TRIM9-low versus TRIM9-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM9→partner) and Y-score (partner→TRIM9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GML →	+0.060	+4.152	.005	.009	3	1
BLOOD_Leukemia	GOLGA6L1 →	+0.043	+5.060	<.001	.001	3	1
LUNG_NSCLC_LUAD	OR1L6 →	+0.014	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	USP17L19 →	+0.005	+5.266	<.001	.001	3	1
LUNG_NSCLC_LUAD	GYPB →	+0.127	+4.544	<.001	.003	3	1
BLOOD_Lymphoma	CABP5 →	+0.019	+5.452	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

GML by TRIM9 expression — BLOOD_Leukemia

Explore this box plot interactively →