TRIM8

Across TCGA patient cohorts, TRIM8 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,277 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TRIM8-associated proteins across cancer lineages are ARL3, TTI1, and MTA1_T564. Each is linked with TRIM8 in more than 5 cancer types. Because this analysis shows association rather than direction, both TRIM8-to-partner and partner-to-TRIM8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRIM8 versus ARL3 in UCEC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM8→partner) and Y-score (partner→TRIM8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ARL3 →	+0.473	+0.576	<.001	<.001	3	6
UCEC	TTI1 →	-0.228	-0.415	.002	.005	3	5
LSCC	MTA1_T564 →	-1.071	-0.521	<.001	<.001	3	5
PDAC	VPS26A →	+0.208	+0.324	.001	<.001	3	5
GBM	ACTR1A →	+0.464	+0.687	<.001	<.001	3	5
GBM	DCTN3 →	+0.330	+0.385	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,277 associations by consensus.

TRIM8 vs ARL3 — UCEC

Explore this scatter interactively →