TRIM75P

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TRIM75P mutation is significantly associated with the RNA expression of many other genes, with 934 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRIM75P-associated genes across cancer lineages are RNA5SP408, RNU6-454P, and RNA5SP427. Each is linked with TRIM75P in more than 2 cancer types. Because this analysis shows association rather than direction, both TRIM75P-to-partner and partner-to-TRIM75P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP408 grouped by TRIM75P-low versus TRIM75P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM75P→partner) and Y-score (partner→TRIM75P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP408 →+0.277+2.727.005.00533
SKCMRNU6-454P →+0.248+4.594<.001.00832
LUSCRNA5SP427 →+0.311+5.148<.001.00231
LUSCTRBV12-2 →+0.213+3.748<.001.00831
LUSCRPL23AP45 →+0.095+4.192<.001.00331
LUSCCNN2P7 →+0.084+5.196.008<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 934 associations by consensus.

RNA5SP408 by TRIM75P expression — UCEC

Box plot of RNA5SP408 in TRIM75P-low vs TRIM75P-high samples in UCEC.

Explore this box plot interactively →

Exploration