TRIM73

Across TCGA pan-cancer cohorts, TRIM73 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated TRIM73 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher TRIM73 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated TRIM73 expression acts as an unfavorable survival marker.

SKCM, COAD, and ACC are the cancer types where TRIM73 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Median	All	0.288	0.731	.002	21	view →
COAD	OS	Median	III,IV	0.157	0.791	.001	17	view →
ACC	DFS	Median	All	0.140	0.594	.035	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

TRIM73–SKCM (DFS)

Open the SKCM breakdown →