TRIM73

Across TCGA cell cohorts, TRIM73 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,394 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRIM73-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Flagellated sperm motility, and Sperm motility. Each is linked with TRIM73 in more than 14 cancer types. Because this analysis shows association rather than direction, both TRIM73-to-partner and partner-to-TRIM73 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by TRIM73-low versus TRIM73-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM73→partner) and Y-score (partner→TRIM73) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of myoblast fusion →	+0.116	+1.043	<.001	<.001	3	15
OESOPHAGUS	Flagellated sperm motility →	-0.129	-1.676	<.001	<.001	3	15
OESOPHAGUS	Sperm motility →	-0.129	-1.676	<.001	<.001	3	15
BREAST	Regulation of myoblast fusion →	+0.104	+1.180	<.001	<.001	3	14
BREAST	Negative regulation of syncytium formation by plasma membrane fusion →	+0.114	+1.024	<.001	<.001	3	14
LUNG_SCLC	Regulation of syncytium formation by plasma membrane fusion →	+0.105	+1.456	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,394 associations by consensus.

Negative regulation of myoblast fusion by TRIM73 expression — BREAST

Explore this box plot interactively →