TRIM71

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TRIM71 mutation is significantly associated with the RNA expression of many other genes, with 4,405 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRIM71-associated genes across cancer lineages are NCAPG, PSMD9, and DNAJC8. Each is linked with TRIM71 in more than 3 cancer types. Because this analysis shows association rather than direction, both TRIM71-to-partner and partner-to-TRIM71 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM71→partner) and Y-score (partner→TRIM71) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMNCAPG →+0.613+2.247.001.00534
SKCMPSMD9 →+0.276+2.641<.001<.00134
SKCMDNAJC8 →+0.444+3.273<.001<.00134
SKCMPSMC3IP →+0.640+2.593<.001<.00134
SKCMNUSAP1 →+0.581+2.553<.001<.00134
SKCMBUB1B →+0.581+1.944.001.00834
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,405 associations by consensus.

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