Across TCGA patient cohorts, TRIM71 mutation is significantly associated with the total protein of many other genes, with 53 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRIM71-associated genes across cancer lineages are FoxM1, ATM, and Caspase-8. Each is linked with TRIM71 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRIM71-to-partner and partner-to-TRIM71 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM71→partner) and Y-score (partner→TRIM71) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.174	+1.884	.048	.030	3	3
UCEC	ATM →	-0.551	-1.986	<.001	.008	3	3
UCEC	Caspase-8 →	-0.241	-3.973	.004	<.001	3	3
UCEC	Cyclin-B1 →	+0.622	+3.807	.001	<.001	3	3
COAD	Claudin-7 →	+0.724	+2.330	.015	.020	3	3
UCEC	EGFR →	-0.179	-1.807	.001	.025	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

Exploration

TRIM71 survival (RNA) · tumor vs normal (RNA) · all TRIM71 data types