TRIM7

Across TCGA cell cohorts, TRIM7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,271 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TRIM7-associated GO terms across cancer lineages are Kinin cascade, Plasma kallikrein-kinin cascade, and Factor XII activation. Each is linked with TRIM7 in more than 7 cancer types. Because this analysis shows association rather than direction, both TRIM7-to-partner and partner-to-TRIM7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Kinin cascade grouped by TRIM7-low versus TRIM7-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM7→partner) and Y-score (partner→TRIM7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Kinin cascade →	+0.910	+1.314	.003	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Plasma kallikrein-kinin cascade →	+0.910	+1.314	.003	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Factor XII activation →	+0.910	+1.314	.003	<.001	3	8
LUNG_SCLC	Positive regulation of fibrinolysis →	+1.109	+1.302	<.001	<.001	3	8
OESOPHAGUS	Immunoglobulin transcytosis in epithelial cells →	-1.246	-1.377	<.001	<.001	3	7
BONE	Hepatocyte apoptotic process →	-0.185	-2.215	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,271 associations by consensus.

Kinin cascade by TRIM7 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →