TRIM7

Across TCGA cell cohorts, TRIM7 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible TRIM7-associated genes across cancer lineages are SULT2A1, PRORY, and HELT. Each is linked with TRIM7 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM7-to-partner and partner-to-TRIM7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SULT2A1 grouped by TRIM7-low versus TRIM7-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM7→partner) and Y-score (partner→TRIM7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	SULT2A1 →	+0.266	+4.269	<.001	.005	3	2
CNS	PRORY →	+0.595	+5.044	<.001	.001	3	1
CNS	HELT →	+0.030	+4.321	<.001	.009	3	1
LARGE_INTESTINE	CCL18 →	+0.097	+4.415	<.001	.007	3	1
OVARY	OR10C1 →	+0.006	+5.807	<.001	.001	3	1
LUNG_NSCLC_LUAD	DAOA →	+0.017	+5.266	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

SULT2A1 by TRIM7 expression — LUNG_SCLC

Explore this box plot interactively →