TRIM7-AS1

Across TCGA pan-cancer cohorts, TRIM7-AS1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of TRIM7-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where TRIM7-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types TRIM7-AS1 is over-expressed in tumor, although a few such as THCA and LUSC show the opposite, repressed pattern.

THCA, LIHC, and COAD are the cancer types where TRIM7-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TRIM7-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	III,IV	−0.231	<.001	7	view →
LIHC	All	All	+0.081	.002	6	view →
COAD	Male	All	+0.166	.019	5	view →
KIRP	Male	III,IV	+0.161	.014	5	view →
KIRC	All	All	+0.085	<.001	4	view →
CHOL	Female	All	+0.153	.033	2	view →
LUSC	Male	III,IV	−0.167	<.001	1	view →
LUAD	Female	All	+0.092	.036	1	view →
HNSC	Male	III,IV	−0.083	.033	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

TRIM7-AS1–THCA

Open the THCA breakdown →