TRIM65

Across TCGA patient cohorts, TRIM65 protein abundance is significantly associated with the RNA expression of many other genes, with 4,948 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TRIM65-associated genes across cancer lineages are SMIM2-AS1, ACSS1, and KCNJ11. Each is linked with TRIM65 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRIM65-to-partner and partner-to-TRIM65 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRIM65 versus SMIM2-AS1 in CCRCC, with a Pearson correlation of -0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM65→partner) and Y-score (partner→TRIM65) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SMIM2-AS1 →	-1.002	-0.164	<.001	.002	3	3
PDAC	ACSS1 →	-0.684	-0.207	<.001	<.001	3	3
LUAD	KCNJ11 →	-0.792	-0.197	<.001	<.001	3	3
GBM	SMIM10L2B →	-0.601	-0.207	.001	<.001	3	3
CCRCC	LINC00484 →	-0.456	-0.174	<.001	<.001	3	3
LUAD	KIF1A →	-0.958	-0.119	.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,948 associations by consensus.

TRIM65 vs SMIM2-AS1 — CCRCC

Explore this scatter interactively →