TRIM65

Across TCGA cell cohorts, TRIM65 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,647 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TRIM65-associated GO terms across cancer lineages are Pre-mRNA catabolic process, Regulation of protein oligomerization, and Positive regulation of protein oligomerization. Each is linked with TRIM65 in more than 16 cancer types. Because this analysis shows association rather than direction, both TRIM65-to-partner and partner-to-TRIM65 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pre-mRNA catabolic process grouped by TRIM65-low versus TRIM65-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM65→partner) and Y-score (partner→TRIM65) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Pre-mRNA catabolic process →	+0.288	+1.394	<.001	<.001	3	17
BONE	Regulation of protein oligomerization →	+0.247	+1.459	<.001	<.001	3	17
BONE	Positive regulation of protein oligomerization →	+0.264	+1.177	<.001	<.001	3	15
BONE	Nucleic acid catabolic process →	+0.049	+0.730	<.001	<.001	3	13
LARGE_INTESTINE	Host-mediated activation of viral process →	+0.079	+0.780	.001	<.001	3	13
BONE	Subtelomeric heterochromatin formation →	+0.157	+1.004	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,647 associations by consensus.

Pre-mRNA catabolic process by TRIM65 expression — BONE

Explore this box plot interactively →