Across TCGA pan-cancer cohorts, TRIM64EP RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of TRIM64EP’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where TRIM64EP RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TRIM64EP is over-expressed in tumor.
LUSC are the cancer types where TRIM64EP tumor–normal differential expression is most reproducible.