Across TCGA pan-cancer cohorts, TRIM64 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated TRIM64 data layer compared with 10 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher TRIM64 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TRIM64 expression acts as an unfavorable survival marker.

ESCA are the cancer types where TRIM64 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Median	II,III,IV	0.103	0.868	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: TRIM64 tumor-vs-normal RNA expression · all TRIM64 data types