TRIM61

Across TCGA pan-cancer cohorts, TRIM61 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated TRIM61 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher TRIM61 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TRIM61 expression acts as an unfavorable survival marker, although some lineages such as HNSC and ACC show a favorable association.

LUSC, HNSC, and LGG are the cancer types where TRIM61 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	All	0.344	0.508	.001	73	view →
HNSC	DFS	Quartile	All	0.420	0.297	<.001	70	view →
LGG	DFS	Tertile	All	0.630	0.797	<.001	35	view →
OV	DFS	Quartile	III,IV	0.455	0.575	.007	28	view →
ACC	OS	Quartile	All	0.773	0.408	.019	25	view →
UVM	DFS	Median	All	0.344	0.628	.004	23	view →
LUAD	OS	Quartile	All	0.788	0.584	.006	19	view →
CESC	DFS	Median	III,IV	0.208	0.580	.005	18	view →
BLCA	OS	Median	III,IV	0.293	0.442	.014	14	view →
SKCM	OS	Tertile	All	0.389	0.281	.012	12	view →
SARC	OS	Tertile	All	0.806	0.654	.008	12	view →
MESO	OS	Quartile	All	0.143	0.638	.026	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

TRIM61–LUSC (OS)

Open the LUSC breakdown →