TRIM60P8Y

Across TCGA patient cohorts, TRIM60P8Y RNA expression is significantly associated with the mutation status of many other genes, with 38 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TRIM60P8Y-associated genes across cancer lineages are NOMO1, VPS18, and CD4. Each is linked with TRIM60P8Y in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM60P8Y-to-partner and partner-to-TRIM60P8Y results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NOMO1 grouped by TRIM60P8Y-low versus TRIM60P8Y-high in BRCA.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM60P8Y→partner) and Y-score (partner→TRIM60P8Y) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NOMO1 →	+9.057	+0.034	.003	<.001	3	1
BRCA	VPS18 →	+7.473	+0.017	.007	<.001	3	1
BRCA	CD4 →	+7.057	+0.013	.009	<.001	3	1
BRCA	HES1 →	+9.057	+0.034	.003	<.001	3	1
BRCA	WIPF1 →	+8.057	+0.023	.005	<.001	3	1
BRCA	DYNC2I2 →	+9.057	+0.034	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

NOMO1 by TRIM60P8Y expression — BRCA

Explore this box plot interactively →