TRIM60P14

Across TCGA pan-cancer cohorts, TRIM60P14 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of TRIM60P14’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where TRIM60P14 RNA is repressed in tumor relative to normal tissue. In most cancer types TRIM60P14 is over-expressed in tumor, although a few such as UCEC and LUSC show the opposite, repressed pattern.

UCEC, LUSC, and HNSC are the cancer types where TRIM60P14 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TRIM60P14 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	All	−0.129	.003	8	view →
LUSC	All	All	−0.058	.005	4	view →
HNSC	Male	All	+0.019	.030	4	view →
PAAD	Female	All	−0.185	.006	2	view →
KICH	Female	All	−0.026	.023	1	view →
BRCA	All	All	−0.020	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

TRIM60P14–UCEC

Open the UCEC breakdown →