TRIM6

Across TCGA patient cohorts, TRIM6 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,838 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TRIM6-associated proteins across cancer lineages are RBMS2, RNH1, and FAM114A1. Each is linked with TRIM6 in more than 5 cancer types. Because this analysis shows association rather than direction, both TRIM6-to-partner and partner-to-TRIM6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRIM6 versus RBMS2 in BRCA, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM6→partner) and Y-score (partner→TRIM6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RBMS2 →	+0.379	+0.782	<.001	<.001	3	6
BRCA	RNH1 →	+0.364	+0.725	<.001	<.001	3	6
OV	FAM114A1 →	+0.383	+0.655	<.001	<.001	3	5
OV	CNN3 →	+0.676	+0.722	<.001	<.001	3	5
LSCC	UNG →	-0.483	-0.436	.004	.001	3	5
OV	WDR1 →	+0.261	+0.442	.005	.005	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,838 associations by consensus.

TRIM6 vs RBMS2 — BRCA

Explore this scatter interactively →