TRIM6

Across TCGA patient cohorts, TRIM6 protein abundance is significantly associated with the RNA expression of many other genes, with 1,289 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TRIM6-associated genes across cancer lineages are TBC1D4, C1QTNF4, and CCDC168. Each is linked with TRIM6 in more than 3 cancer types. Because this analysis shows association rather than direction, both TRIM6-to-partner and partner-to-TRIM6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRIM6 versus TBC1D4 in BRCA, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM6→partner) and Y-score (partner→TRIM6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TBC1D4 →	+0.994	+1.077	.002	.008	3	4
BRCA	C1QTNF4 →	-0.418	-0.692	.005	.008	3	2
CCRCC	CCDC168 →	+0.069	+0.283	.002	.002	3	2
BRCA	OST4 →	-0.567	-0.971	.003	.002	3	2
HNSC	LINC02652 →	+0.635	+1.033	.007	.009	3	2
BRCA	ASAP3 →	-0.752	-0.881	.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,289 associations by consensus.

TRIM6 vs TBC1D4 — BRCA

Explore this scatter interactively →