Across TCGA cell cohorts, TRIM59 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,088 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TRIM59-associated GO terms across cancer lineages are Protein localization to condensed chromosome, Positive regulation of maintenance of sister chromatid cohesion, and Positive regulation of maintenance of mitotic sister chromatid cohesion. Each is linked with TRIM59 in more than 12 cancer types. Because this analysis shows association rather than direction, both TRIM59-to-partner and partner-to-TRIM59 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM59→partner) and Y-score (partner→TRIM59) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Protein localization to condensed chromosome →	+0.103	+0.884	.004	<.001	3	13
BLOOD_Lymphoma	Positive regulation of maintenance of sister chromatid cohesion →	+0.082	+1.032	<.001	<.001	3	12
BLOOD_Lymphoma	Positive regulation of maintenance of mitotic sister chromatid cohesion →	+0.082	+1.032	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair →	+0.072	+1.041	<.001	.002	3	11
BLOOD_Lymphoma	Mitotic sister chromatid segregation →	+0.078	+1.036	<.001	<.001	3	11
BLOOD_Myeloma	Regulation of mitotic sister chromatid separation →	+0.124	+1.059	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,088 associations by consensus.

Exploration

TRIM59 survival (RNA) · tumor vs normal (RNA) · all TRIM59 data types