Across TCGA patient cohorts, TRIM52 mutation is significantly associated with the RNA expression of many other genes, with 367 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRIM52-associated genes across cancer lineages are SLC27A4, PRPS1P1, and UQCRC1. Each is linked with TRIM52 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM52-to-partner and partner-to-TRIM52 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM52→partner) and Y-score (partner→TRIM52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SLC27A4 →	+0.513	+3.409	.008	.004	3	2
UCEC	PRPS1P1 →	+0.081	+2.775	.008	.002	3	2
UCEC	UQCRC1 →	+0.578	+3.649	.001	.001	3	2
UCEC	MRPL37 →	+0.669	+3.507	<.001	.002	3	2
UCEC	COPS3 →	+0.645	+3.584	<.001	.003	3	2
COAD	RNU6-633P →	+0.538	+3.789	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 367 associations by consensus.

Exploration

TRIM52 survival (RNA) · tumor vs normal (RNA) · all TRIM52 data types