Across TCGA patient cohorts, TRIM52 mutation is significantly associated with the immune_cell of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRIM52-associated genes across cancer lineages are Keratinocytes, MEP, and Mesangial cells. Each is linked with TRIM52 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM52-to-partner and partner-to-TRIM52 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM52→partner) and Y-score (partner→TRIM52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Keratinocytes →	+0.015	+2.588	.029	.009	3	1
UCEC	MEP →	+0.041	+3.354	.002	.005	3	1
UCEC	Mesangial cells →	-0.044	-2.936	.019	.036	3	1
UCEC	Sebocytes →	+0.030	+3.201	.011	.009	3	1
UCEC	CD8+ naive T-cells →	+0.039	+3.186	.002	.010	2	1
UCEC	Th2 cells →	+0.298	+3.177	<.001	.010	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

TRIM52 survival (RNA) · tumor vs normal (RNA) · all TRIM52 data types