TRIM52-AS1

Across TCGA pan-cancer cohorts, TRIM52-AS1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated TRIM52-AS1 data layer.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher TRIM52-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated TRIM52-AS1 expression acts as an unfavorable survival marker, although some lineages such as CHOL and LGG show a favorable association.

CHOL, LIHC, and ACC are the cancer types where TRIM52-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CHOL	OS	Median	II,III,IV	0.799	0.246	.002	42	view →
LIHC	DFS	Tertile	All	0.462	0.673	<.001	37	view →
ACC	OS	Tertile	II,III,IV	0.193	0.713	.006	35	view →
LGG	DFS	Tertile	All	0.867	0.766	.009	23	view →
UCS	DFS	Quartile	III,IV	0.541	0.159	.018	20	view →
SKCM	DFS	Median	III,IV	0.694	0.490	.005	18	view →
KICH	OS	Quartile	III,IV	0.388	0.876	.022	17	view →
LUSC	DFS	Quartile	III,IV	0.334	0.772	<.001	16	view →
THYM	OS	Median	II,III,IV	1.000	0.889	.013	12	view →
MESO	OS	Median	All	0.712	0.308	.004	12	view →
ESCA	OS	Tertile	II,III,IV	0.803	0.602	.020	12	view →
PAAD	OS	Quartile	All	0.615	0.262	.010	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

TRIM52-AS1–CHOL (OS)

Open the CHOL breakdown →