TRIM51JP

Across TCGA pan-cancer cohorts, TRIM51JP RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of TRIM51JP’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TRIM51JP RNA is repressed in tumor relative to normal tissue. In most cancer types TRIM51JP is over-expressed in tumor, although a few such as KIRC and THCA show the opposite, repressed pattern.

KIRC, THCA, and UCEC are the cancer types where TRIM51JP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TRIM51JP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	−0.039	<.001	9	view →
THCA	Female	III,IV	−0.152	.016	4	view →
UCEC	All	All	+0.083	.023	4	view →
PAAD	Female	All	−0.075	.037	2	view →
KICH	All	All	−0.071	.012	2	view →
HNSC	Male	All	−0.032	.026	1	view →
LIHC	All	All	+0.012	.024	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

TRIM51JP–KIRC

Open the KIRC breakdown →