TRIM51EP

Across TCGA pan-cancer cohorts, TRIM51EP RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated TRIM51EP data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher TRIM51EP RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TRIM51EP expression acts as an unfavorable survival marker, although some lineages such as SKCM and LUAD show a favorable association.

LIHC, MESO, and THCA are the cancer types where TRIM51EP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Tertile	II,III,IV	0.051	0.716	<.001	90	view →
MESO	DFS	Tertile	All	0.090	0.369	.001	54	view →
THCA	OS	Tertile	III,IV	0.171	0.788	<.001	36	view →
DLBC	OS	Tertile	II,III,IV	0.118	0.802	.025	27	view →
BLCA	OS	Tertile	IV	0.192	0.494	.006	9	view →
SKCM	OS	Tertile	II,III,IV	1.000	0.821	.023	6	view →
LUAD	OS	Tertile	II,III,IV	0.713	0.527	.043	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

TRIM51EP–LIHC (OS)

Open the LIHC breakdown →