TRIM51DP

Across TCGA pan-cancer cohorts, TRIM51DP RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated TRIM51DP data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher TRIM51DP RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TRIM51DP expression acts as an unfavorable survival marker, although some lineages such as LGG and ESCA show a favorable association.

SKCM, KIRP, and STAD are the cancer types where TRIM51DP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Tertile	II,III,IV	0.098	0.246	<.001	78	view →
KIRP	DFS	Tertile	All	0.038	0.920	<.001	60	view →
STAD	DFS	Tertile	All	0.471	0.676	.001	45	view →
BLCA	OS	Tertile	All	0.388	0.624	.036	27	view →
DLBC	OS	Tertile	II,III,IV	0.118	0.802	.025	24	view →
LUSC	DFS	Tertile	All	0.218	0.412	.016	18	view →
PCPG	DFS	Tertile	All	0.794	0.934	.028	12	view →
LIHC	OS	Tertile	All	0.144	0.704	.016	9	view →
LGG	OS	Median	All	0.934	0.850	.017	7	view →
BRCA	DFS	Tertile	All	0.373	0.535	.037	6	view →
ESCA	OS	Tertile	All	0.920	0.676	.037	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

TRIM51DP–SKCM (DFS)

Open the SKCM breakdown →