TRIM51

Across TCGA patient cohorts, TRIM51 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,357 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TRIM51-associated GO terms across cancer lineages are Establishment of protein localization to membrane, Regulation of microtubule polymerization or depolymerization, and Regulation of protein ubiquitination. Each is linked with TRIM51 in more than 7 cancer types. Because this analysis shows association rather than direction, both TRIM51-to-partner and partner-to-TRIM51 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to membrane grouped by TRIM51-low versus TRIM51-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM51→partner) and Y-score (partner→TRIM51) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Establishment of protein localization to membrane →	+0.118	+0.059	<.001	.003	3	7
STAD	Regulation of microtubule polymerization or depolymerization →	+0.087	+0.032	<.001	.002	3	7
STAD	Regulation of protein ubiquitination →	+0.117	+0.054	<.001	<.001	3	7
STAD	Ribosomal large subunit biogenesis →	+0.135	+0.031	<.001	.003	3	7
STAD	Positive regulation of post-translational protein modification →	+0.111	+0.055	<.001	.005	2	8
STAD	Regulation of cyclin-dependent protein kinase activity →	+0.096	+0.030	<.001	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,357 associations by consensus.

Establishment of protein localization to membrane by TRIM51 expression — STAD

Explore this box plot interactively →