TRIM51

Across TCGA cell cohorts, TRIM51 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,117 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TRIM51-associated GO terms across cancer lineages are Chemokine (C-X-C motif) ligand 12 signaling pathway, Response to lithium ion, and Cardiac muscle adaptation. Each is linked with TRIM51 in more than 3 cancer types. Because this analysis shows association rather than direction, both TRIM51-to-partner and partner-to-TRIM51 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chemokine (C-X-C motif) ligand 12 signaling pathway grouped by TRIM51-low versus TRIM51-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM51→partner) and Y-score (partner→TRIM51) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Chemokine (C-X-C motif) ligand 12 signaling pathway →	-0.141	-0.060	.007	.009	3	4
SKIN	Response to lithium ion →	-0.116	-1.537	<.001	.001	3	3
SKIN	Cardiac muscle adaptation →	+0.081	+1.401	.008	.006	3	3
SKIN	Cardiac muscle hypertrophy in response to stress →	+0.081	+1.401	.008	.006	3	3
SKIN	Regulation of microglial cell activation →	-0.112	-1.897	.001	<.001	3	3
SKIN	Negative regulation of microglial cell activation →	-0.124	-1.362	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,117 associations by consensus.

Chemokine (C-X-C motif) ligand 12 signaling pathway by TRIM51 expression — BONE

Explore this box plot interactively →