Across TCGA cell cohorts, TRIM49D1 RNA expression is significantly associated with the drug of many other genes, with 55 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TRIM49D1-associated genes across cancer lineages are Camptothecin, Quizartinib, and Linifanib. Each is linked with TRIM49D1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRIM49D1-to-partner and partner-to-TRIM49D1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM49D1→partner) and Y-score (partner→TRIM49D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Camptothecin →	+0.736	+0.040	.008	.023	3	3
LARGE_INTESTINE	Quizartinib →	-0.464	-0.005	.016	.035	3	3
LARGE_INTESTINE	Linifanib →	-0.424	-0.005	.025	.035	3	3
LARGE_INTESTINE	XMD15-27 →	-0.357	-0.005	.013	.035	3	3
LUNG_SCLC	Talazoparib →	+0.944	+0.041	.011	.024	3	2
LUNG_SCLC	SN-38 →	+0.889	+0.043	.003	.015	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 55 associations by consensus.

Exploration

TRIM49D1 survival (RNA) · tumor vs normal (RNA) · all TRIM49D1 data types