TRIM47

Across TCGA cell cohorts, TRIM47 mutation is significantly associated with the RNA expression of many other genes, with 35 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRIM47-associated genes across cancer lineages are C6orf118, OR1L6, and PRAMEF20. Each is linked with TRIM47 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM47-to-partner and partner-to-TRIM47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C6orf118 grouped by TRIM47-low versus TRIM47-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM47→partner) and Y-score (partner→TRIM47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C6orf118 →	+0.130	+3.115	<.001	.004	3	1
LARGE_INTESTINE	OR1L6 →	+0.015	+3.700	<.001	.009	3	1
LARGE_INTESTINE	PRAMEF20 →	+0.008	+3.700	<.001	.009	3	1
BLOOD_Leukemia	EPPIN →	+0.004	+3.922	.004	.002	3	1
BLOOD_Leukemia	GML →	+0.065	+3.567	<.001	.003	3	1
BLOOD_Leukemia	SYT10 →	+0.346	+3.339	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

C6orf118 by TRIM47 expression — LARGE_INTESTINE

Explore this box plot interactively →