TRIM44

Across TCGA pan-cancer cohorts, TRIM44 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated TRIM44 data layer compared with 24 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher TRIM44 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated TRIM44 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

LUAD, CCRCC, and PDAC are the cancer types where TRIM44 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	III,IV	0.854	0.346	.004	16	view →
CCRCC	DFS	Tertile	II,III,IV	0.780	1.000	.014	8	view →
PDAC	OS	Quartile	All	0.337	0.785	.038	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

TRIM44–LUAD (DFS)

Open the LUAD breakdown →