TRIM44

Across TCGA cell cohorts, TRIM44 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,211 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TRIM44-associated GO terms across cancer lineages are Regulation of protein K48-linked ubiquitination, Response to oscillatory fluid shear stress, and Cellular response to oscillatory fluid shear stress. Each is linked with TRIM44 in more than 17 cancer types. Because this analysis shows association rather than direction, both TRIM44-to-partner and partner-to-TRIM44 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein K48-linked ubiquitination grouped by TRIM44-low versus TRIM44-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM44→partner) and Y-score (partner→TRIM44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of protein K48-linked ubiquitination →	+0.201	+2.069	<.001	<.001	3	18
STOMACH	Response to oscillatory fluid shear stress →	+0.226	+1.902	<.001	<.001	3	16
STOMACH	Cellular response to oscillatory fluid shear stress →	+0.226	+1.902	<.001	<.001	3	16
STOMACH	Vascular endothelial cell response to oscillatory fluid shear stress →	+0.226	+1.902	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Response to dehydroepiandrosterone →	+0.215	+1.983	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Protein stabilization →	+0.068	+1.576	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,211 associations by consensus.

Regulation of protein K48-linked ubiquitination by TRIM44 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →