TRIM44

Across TCGA cell cohorts, TRIM44 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TRIM44-associated genes across cancer lineages are GJD2, TAFA1, and NAT8B. Each is linked with TRIM44 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM44-to-partner and partner-to-TRIM44 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GJD2 grouped by TRIM44-low versus TRIM44-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM44→partner) and Y-score (partner→TRIM44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GJD2 →	+0.002	+3.700	<.001	.009	3	1
LARGE_INTESTINE	TAFA1 →	+0.234	+3.103	.002	.004	3	1
LARGE_INTESTINE	NAT8B →	+0.706	+3.667	.003	.003	3	1
LARGE_INTESTINE	PTX4 →	+0.101	+3.520	.001	.005	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

GJD2 by TRIM44 expression — LARGE_INTESTINE

Explore this box plot interactively →