TRIM43B

Across TCGA pan-cancer cohorts, TRIM43B RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated TRIM43B data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher TRIM43B RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TRIM43B expression acts as an unfavorable survival marker, although some lineages such as OV show a favorable association.

COAD, GBM, and CESC are the cancer types where TRIM43B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	II,III,IV	0.157	0.655	<.001	72	view →
GBM	OS	Tertile	All	0.253	0.435	.003	45	view →
CESC	DFS	Tertile	II,III,IV	0.353	0.728	.001	36	view →
BLCA	DFS	Tertile	IV	0.094	0.466	.031	9	view →
CHOL	OS	Tertile	All	0.155	0.725	.029	9	view →
KIRC	DFS	Tertile	IV	0.144	0.345	.047	6	view →
OV	DFS	Tertile	IV	0.430	0.231	.039	6	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

TRIM43B–COAD (DFS)

Open the COAD breakdown →