TRIM42

Across TCGA patient cohorts, TRIM42 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,131 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TRIM42-associated GO terms across cancer lineages are DNA modification, Regulation of transcription elongation by RNA polymerase II, and Positive regulation of DNA metabolic process. Each is linked with TRIM42 in more than 11 cancer types. Because this analysis shows association rather than direction, both TRIM42-to-partner and partner-to-TRIM42 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA modification grouped by TRIM42-low versus TRIM42-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM42→partner) and Y-score (partner→TRIM42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	DNA modification →	+0.066	+0.075	<.001	<.001	3	12
STAD	Regulation of transcription elongation by RNA polymerase II →	+0.085	+0.064	<.001	<.001	3	11
STAD	Positive regulation of DNA metabolic process →	+0.079	+0.075	<.001	<.001	3	11
STAD	Nucleus organization →	+0.080	+0.075	<.001	<.001	3	11
STAD	Spindle organization →	+0.087	+0.075	<.001	<.001	3	11
STAD	Positive regulation of protein-containing complex assembly →	+0.071	+0.051	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,131 associations by consensus.

DNA modification by TRIM42 expression — STAD

Explore this box plot interactively →