TRIM41

Across TCGA pan-cancer cohorts, TRIM41 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TRIM41 data layer compared with 26 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher TRIM41 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated TRIM41 expression acts as an unfavorable survival marker, although some lineages such as LUAD and PDAC show a favorable association.

LUAD, PDAC, and UCEC are the cancer types where TRIM41 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	II,III,IV	0.784	0.431	.017	10	view →
PDAC	OS	Median	III,IV	0.669	0.191	.006	9	view →
UCEC	DFS	Median	II,III,IV	0.550	0.865	.027	4	view →
HNSC	DFS	Median	III,IV	0.915	1.000	.008	2	view →
CCRCC	OS	Quartile	III,IV	0.712	1.000	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TRIM41–LUAD (OS)

Open the LUAD breakdown →