TRIM41

Across TCGA patient cohorts, TRIM41 mutation is significantly associated with the RNA expression of many other genes, with 3,749 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRIM41-associated genes across cancer lineages are RNU7-119P, RNU6-364P, and CCNG1P1. Each is linked with TRIM41 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRIM41-to-partner and partner-to-TRIM41 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU7-119P grouped by TRIM41-low versus TRIM41-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM41→partner) and Y-score (partner→TRIM41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU7-119P →	+0.498	+5.039	<.001	.003	3	3
OV	RNU6-364P →	+0.232	+6.523	<.001	<.001	3	2
OV	CCNG1P1 →	+0.118	+4.598	<.001	.004	3	2
OV	RNU6-1052P →	+0.451	+5.095	<.001	.001	3	2
OV	GTF3AP2 →	+0.206	+4.374	<.001	.006	3	2
BLCA	RNU7-56P →	+0.329	+4.147	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,749 associations by consensus.

RNU7-119P by TRIM41 expression — SKCM

Explore this box plot interactively →