TRIM41

Across TCGA cell cohorts, TRIM41 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,799 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRIM41-associated GO terms across cancer lineages are mRNA splice site recognition, Viral translational termination-reinitiation, and Metaphase/anaphase transition of mitotic cell cycle. Each is linked with TRIM41 in more than 15 cancer types. Because this analysis shows association rather than direction, both TRIM41-to-partner and partner-to-TRIM41 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA splice site recognition grouped by TRIM41-low versus TRIM41-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM41→partner) and Y-score (partner→TRIM41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	mRNA splice site recognition →	+0.177	+1.215	<.001	<.001	3	16
BONE	Viral translational termination-reinitiation →	+0.098	+0.750	<.001	<.001	3	16
BONE	Metaphase/anaphase transition of mitotic cell cycle →	+0.230	+0.793	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Membrane raft localization →	-0.235	-0.874	<.001	.001	3	15
LARGE_INTESTINE	Nucleic acid catabolic process →	+0.050	+0.771	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Microtubule nucleation →	+0.124	+1.179	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,799 associations by consensus.

mRNA splice site recognition by TRIM41 expression — OESOPHAGUS

Explore this box plot interactively →