TRIM40

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TRIM40 mutation is significantly associated with the RNA expression of many other genes, with 632 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRIM40-associated genes across cancer lineages are RNA5SP422, HMGN1P30, and ELOVL7. Each is linked with TRIM40 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRIM40-to-partner and partner-to-TRIM40 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM40→partner) and Y-score (partner→TRIM40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP422 →+0.698+2.408.006.00933
SKCMHMGN1P30 →+0.243+3.371<.001<.00132
UCECELOVL7 →+1.075+3.332.002.00532
UCECRNU7-10P →+0.627+2.575<.001.00632
LUADHSD3BP1 →+0.368+4.510<.001.00532
LUADOSBPL9P1 →+0.037+5.076<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 632 associations by consensus.

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