TRIM40

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TRIM40 mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRIM40-associated genes across cancer lineages are TFRC, ASNS, and EGFR_pY1068. Each is linked with TRIM40 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM40-to-partner and partner-to-TRIM40 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM40→partner) and Y-score (partner→TRIM40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTFRC →+0.682+3.000.026.03732
UCECASNS →+0.482+3.000.021.03731
UCECEGFR_pY1068 →-0.357-3.000.013.03621
UCECp38-MAPK_pT180_Y182 →-0.678-2.986.009.03721
UCECP-Cadherin →-0.172-2.986.039.03711
UCECPCNA →+0.270+3.000.030.03711
Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration