Across TCGA cell cohorts, TRIM40 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRIM40-associated genes across cancer lineages are C1QTNF7, ACER1, and CLEC4C. Each is linked with TRIM40 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM40-to-partner and partner-to-TRIM40 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM40→partner) and Y-score (partner→TRIM40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C1QTNF7 →	+0.130	+4.108	<.001	.008	3	1
LARGE_INTESTINE	ACER1 →	+0.161	+3.823	<.001	.006	3	1
SKIN	CLEC4C →	+0.040	+4.977	<.001	.007	3	1
SKIN	OPN1MW3 →	+0.013	+6.022	<.001	.001	3	1
BLOOD_Leukemia	ASZ1 →	+0.119	+4.152	.001	.009	3	1
BLOOD_Leukemia	CST2 →	+0.491	+4.152	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

TRIM40 survival (RNA) · tumor vs normal (RNA) · all TRIM40 data types