TRIM4

Across TCGA patient cohorts, TRIM4 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,806 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TRIM4-associated proteins across cancer lineages are SBDS, MEPCE, and DNAJC1. Each is linked with TRIM4 in more than 6 cancer types. Because this analysis shows association rather than direction, both TRIM4-to-partner and partner-to-TRIM4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRIM4 versus SBDS in GBM, with a Pearson correlation of 0.20.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM4→partner) and Y-score (partner→TRIM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SBDS →	+0.257	+0.353	.001	<.001	3	7
LSCC	MEPCE →	+0.359	+0.419	<.001	<.001	3	6
LSCC	DNAJC1 →	-0.419	-0.362	<.001	<.001	3	6
HNSC	GTF2I →	+0.420	+0.514	<.001	.003	3	6
COAD	YWHAG →	+0.233	+0.365	<.001	<.001	3	6
COAD	PURB →	+0.267	+0.483	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,806 associations by consensus.

TRIM4 vs SBDS — GBM

Explore this scatter interactively →