TRIM4

Across TCGA patient cohorts, TRIM4 protein abundance is significantly associated with the RNA expression of many other genes, with 11,104 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TRIM4-associated genes across cancer lineages are PAK1IP1, KCTD12, and DNMT3B. Each is linked with TRIM4 in more than 3 cancer types. Because this analysis shows association rather than direction, both TRIM4-to-partner and partner-to-TRIM4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRIM4 versus PAK1IP1 in UCEC, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM4→partner) and Y-score (partner→TRIM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PAK1IP1 →	-0.719	-0.240	<.001	.005	3	4
UCEC	KCTD12 →	+0.639	+0.306	.004	<.001	3	4
LUAD	DNMT3B →	-0.734	-0.148	<.001	.001	3	4
LSCC	SRPK1 →	-0.538	-0.150	.001	.003	3	4
LUAD	P2RX7 →	+0.661	+0.185	<.001	<.001	3	4
LSCC	E2F1 →	-1.117	-0.221	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,104 associations by consensus.

TRIM4 vs PAK1IP1 — UCEC

Explore this scatter interactively →