TRIM36

Across TCGA pan-cancer cohorts, TRIM36 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TRIM36 data layer compared with 23 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher TRIM36 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated TRIM36 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

GBM, UCEC, and LUAD are the cancer types where TRIM36 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	OS	Quartile	All	0.223	0.694	.022	12	view →
UCEC	DFS	Tertile	II,III,IV	1.000	0.469	.015	4	view →
LUAD	OS	Median	All	0.627	0.862	.030	2	view →
LSCC	DFS	Median	II,III,IV	0.566	0.794	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

TRIM36–GBM (OS)

Open the GBM breakdown →